Improving IVF outcomes by better embryo selection
- PGS helps find embryos with the right number of chromosomes.
- Preimplantation Genetic Screening can be used to screen embryos for the right number of chromosomes to increase the chance that a viable embryo is selected for transfer. This has been shown to increase the chance of a successful pregnancy.
- Normal embryos have a higher chance of implantation and the resulting pregnancy has a higher chance of success.
- A recent study showed: Pregnancy rates improved 65% when embryos selected for transfer were screened for normal chromosome numbers compared to conventional morphology methods.
Transferring a single embryo reduces risks.
- The use of PGS may mean that only a single embryo is transferred: Reducing the likelihood of multiple births and the associated increased risk of complications to mother and children.
- The right number of is chromosomes may be critical to IVF success.
- Chromosomes carry the genes that guide the growth of an embryo into a baby.
Having missing or extra chromosomes is called aneuploidy (an-yu-ploy-dee).
- Most embryos with aneuploidy will not implant or will miscarry during the first trimester of pregnancy.
- Some aneuploid embryos result in the birth of a baby with a genetic abnormality – one of the most common is Down Syndrome, caused by an extra copy of chromosome 21.
- The risk of aneuploidy increases with the mother’s age. This is one of the reasons why women in their late 30s and early 40s have more risk of miscarriage and less chance of getting pregnant.
Transferring an embryo with an abnormal number of chromosomes reduces the chance of a successful pregnancy. In the lab, it can be hard to tell which embryos have the correct number of chromosomes.
How PGS works
Ask your doctor if PGS is right for you!
For more information visit : Illumina PGS
Add a Comment